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CINV Risk Factors

Patient-specific risk factors and therapy-specific risk factors will play a role in whether you experience nausea and vomiting. It is important to remember that not all people undergoing chemotherapy experience nausea and vomiting.

Patient-Specific Risk Factors

You may experience CINV if:

  • you are younger than age 50

  • you are female

  • you had nausea and vomiting during previous chemotherapy treatments

  • you experienced sweating, dizziness, or warmth after your last chemotherapy treatment

In addition, nausea and vomiting are actually less likely to affect people who have a history of chronic alcohol use over many years.

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Therapy-Specific Risk Factors

The dose and the way chemotherapy drugs are given can affect your potential for experiencing CINV:

  • Higher doses of chemotherapy are more likely to cause CINV

  • Your treatment schedule, which is the time of day and how often you take the drug, may cause CINV. For example, chemotherapy given in the morning is more likely to cause CINV. Treatments given at short intervals - one treatment close to another - are more likely to cause CINV since there is less time to recover from the nausea and vomiting.

  • A chemotherapy drug injected into a vein (intravenously) may cause CINV sooner than a drug given by mouth (orally), or injected into a muscle because it is absorbed more quickly into the bloodstream.

If you are receiving both chemotherapy and radiation therapy, you may be at higher risk of experiencing nausea and vomiting.

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