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Anticipatory Onset Nausea and Vomiting

Anticipatory Onset Nausea and Vomiting:

  • is nausea and vomiting that happens before or "in anticipation of" chemotherapy

  • is a learned reaction that results when severe nausea and vomiting are experienced during previous chemotherapy treatments

Preventing CINV is the best way to avoid anticipatory CINV.

Because the brain's Chemoreceptor Trigger Zone does not control anticipatory CINV, the condition usually is not treated with antiemetic drugs. Behavioral therapies like hypnosis, relaxation, and guided imagery, have shown some success in relieving anticipatory CINV. In some cases, antianxiety drugs such as the benzodiazepines may be used.

Click here to view a table listing the antiemetic drugs commonly used to prevent and treat CINV.

Checklist of Questions About Your Medicine

Regardless of the kind of chemotherapy you are taking or the type of CINV diagnosed, ask your doctor the following questions about any medicine they might be considering to control your nausea and vomiting:

  • How many times a day do I need to take my medicine?

  • Can I have the medicine that is easiest for me to take (especially if I am already taking other medicines)?

  • Can I have a medicine that is least likely to interact with other medicines I am taking?

  • Is my medicine OK to take if I have other conditions (such as a heart, liver or kidney condition)?

  • What happens if I forget to take it on time?

  • What if it begins to wear off and I feel sick? Can I take another one?

  • Will I be free of symptoms day and night?

  • Who should I tell if my medicine doesn’t work?

  • Are there any side effects from the medicine?

  • What alternative medicines are there if my medicine does not provide full 24-hour control or relief of my nausea and vomiting (for example, if I wake up at night feeling sick, or feel sick before it’s time to take my next dose of medicine)

And remember: ALWAYS tell your doctor, nurse and pharmacist about ALL the medications you are taking — including over-the-counter medications and dietary supplements.

 

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